May 26, 2023

Recombinant small molecule collagen was successfully included in the International Name of Cosmetic Ingredients (INCI) catalog

We are delighted to announce that Trautec (Jiangsu Chuangjian Medical Technology Co., Ltd.) has achieved a significant milestone in the cosmetics industry. Our cutting-edge recombinant Type III small molecule collagen, trademarked as "ReCol3-TTA03-02SC" with the INCI designation "sr-(sh-Polypeptide -69 Dipeptide-19)," has received official approval for inclusion in the International Cosmetic Ingredients (INCI) catalog, a globally recognized reference used by the cosmetics and personal care industry to identify and standardize ingredients.

This milestone underscores the growing prominence and acceptance of this innovative collagen variant within the cosmetics and skincare product formulation community, further validating its potential for enhancing the quality and efficacy of beauty and personal care products. This achievement underscores the widespread acceptance of our recombinant Type III small molecule collagen as a safe, reliable, and effective ingredient in the realm of cosmetics both domestically and internationally.

Recombinant type III small molecule collagen. Unlock the "core" power of collagen skin care.

We are committed to advancing the science of skincare and beauty, and our inclusion in the INCI catalog is a testament to our dedication to providing consistent ingredients of superior quality for the global cosmetics market. We look forward to continuing our journey of innovation and excellence in the pursuit of regenerative, more radiant skin for all.

Recombinant Type III small molecule collagen holds the key to unlocking the core potential of collagen-based skincare. Recognized as a functional protein, collagen plays a pivotal role in cosmetics by providing anti-wrinkle benefits, aiding in skin barrier repair, and delivering superior moisturization. This has garnered significant attention across the beauty, skincare, and general health industries. Our innovation enhances the effectiveness and absorption of collagen in cosmetic products, elevating the standards of skincare and setting new benchmarks for the industry.

Trautec pioneers the development of recombinant Type III small molecule collagen through cutting-edge techniques in synthetic biology. This innovation involves the precise selection of biologically active, amino acid sequence-enriched fragments from human Type III collagen. Utilizing advanced microbial chassis organisms, and employing high-density expression within yeast, specifically Pichia, we engineer a unique, high-performance recombinant collagen with an astonishingly low molecular weight of just 5kd. This groundbreaking product exhibits exceptional penetration and absorption capabilities, driven by its homology with the human collagen structure.

Pain Point Solutions

  • The amino acid sequence selects the highly active site of human type III collagen, which has strong cell adhesion and integrin binding functions;
  • Small molecular weight (5kDa), easier to be absorbed through the skin, which is beneficial to direct local collagen supplement;
  • Use the concept of synthetic biology to create small molecule-specific chassis microorganisms, which can achieve high-density and high-expression industrial production;
  • Excellent efficacy: It can achieve micro-efficiency in anti-wrinkle, soothing and repairing, and can exert significant effects at a concentration of 0.05%.
Efficacy mechanism of action. High-end, multi-dimensional, precise anti-aging.

Extensive experimentation using diverse Ex vivo and In-vitro models has unequivocally demonstrated the remarkable qualities of Trautec's recombinant Type III small molecule collagen. This innovative collagen swiftly permeates both the dermis and epidermis, boasting exceptional penetration capabilities. It excels in thwarting collagen photoaging damage, curbing the secretion of inflammatory factors, and regulating protein expression to fortify the skin's barrier. Crucially, it has undergone rigorous non-animal testing, affirming its safety profile, which includes an absence of allergy risks and skin and eye irritation. Trautec's recombinant Type III small molecule collagen has reached a stage of standardized mass production and is now a preferred supplier for internationally renowned top-tier brands.

In addition to this, we are thrilled to announce the launch of Trautec's comprehensive, one-stop raw material customization services this year. This service empowers our valued partners with tailored solutions custom-built to their unique application scenarios. Trautec is fully committed to the "made-to-order" approach, and we eagerly await your customization needs.

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