6.01kDa Velastein™
Multi-Active Site Targeted Empowerment

100% Homologousto Human Elastin

Recombinant Elastin

6.01 kDa bioactive recombinant elastin for firmer, more elastic-looking skin

Anti-Aging

Promote skin elasticity by providing a firming touch for a radiant and glowing complexion

Elasticity Support and Skin Firmness

Supports the integrity of the skin’s elastic network, helping to improve firmness, enhance elasticity, and maintain structural resilience.

Vegan + Halal and GMP Certified

Velastein™ eliminates potential risks and biosafety concerns associated with collagens sourced from animals.

Why Elastin Matters?

As skin ages, the elastic fiber system becomes damaged. Intrinsic aging can lead to fiber atrophy and loss of vertical support, while photoaging causes abnormal elastin accumulation and disordered fiber arrangement. These changes are associated with reduced elasticity, sagging, roughness, and deeper wrinkles.

Intracellular Synthetic Pathway of Elastic Fibers

  • Microfibril Assembly: Fibrillin-1 assembles to form microfibrils.
  • Tropoelastin Synthesis: Tropoelastin (TE) monomers are synthesized in the endoplasmic reticulum (ER) and bind to its chaperone EBP (Elastin-binding protein).
  • Secretion and TransportTE-EBP: TE–EBP is transported via the Golgi and secreted.
  • Dissociation and Initiation of Cross-LinkingTE: E dissociates from EBP; Fibulin-4 organizes TE, and LOX drives cross-linking.
  • Microfibril Polymerization Fibulin-5: Fibulin-5 guides elastin to integrate into the microfibril scaffold.
  • Elastic Fiber Maturation: Elastin clusters undergo further aggregation and cross-linking.

Visible Elasticity Improvement Over Time

Human efficacy testing showed multi-dimensional improvement in skin elasticity from Day 0 to Day 28 in the sample containing 0.1% Velastein™.

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